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Antimicrobial Agents and Chemotherapy, May 2009, p. 2192-2195, Vol. 53, No. 5
0066-4804/09/$08.00+0     doi:10.1128/AAC.01543-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Activity Profile In Vitro of Micafungin against Spanish Clinical Isolates of Common and Emerging Species of Yeasts and Molds{triangledown}

Manuel Cuenca-Estrella,* Alicia Gomez-Lopez, Emilia Mellado, Araceli Monzon, Maria J. Buitrago, and Juan L. Rodriguez-Tudela

Mycology Department, Spanish National Center for Microbiology, Instituto de Salud Carlos III, Madrid, Spain

Received 19 November 2008/ Returned for modification 24 January 2009/ Accepted 4 February 2009

A collection of 2,278 isolates belonging to 86 different fungal species was tested with micafungin and eight other drugs using the EUCAST procedures. Micafungin was active against species of Candida and Aspergillus (even azole-resistant species) as well as Penicillium spp., Scedosporium apiospermum, and Acremonium spp. It was inactive for species of Basidiomycota and Mucorales and for multiresistant species such as those of Fusarium.

* Corresponding author. Mailing address: Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo Km 2, 28220 Majadahonda, Madrid, Spain. Phone: 34-91-8223661. Fax: 34-91-5097966. E-mail: mcuenca-estrella{at}isciii.es

{triangledown} Published ahead of print on 17 February 2009.

Antimicrobial Agents and Chemotherapy, May 2009, p. 2192-2195, Vol. 53, No. 5
0066-4804/09/$08.00+0     doi:10.1128/AAC.01543-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Alcazar-Fuoli, L., Mellado, E., Alastruey-Izquierdo, A., Cuenca-Estrella, M., Rodriguez-Tudela, J. L. (2009). Species Identification and Antifungal Susceptibility Patterns of Species Belonging to Aspergillus Section Nigri. Antimicrob. Agents Chemother. 53: 4514-4517 [Abstract] [Full Text]  


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