This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Google Scholar
Right arrow Articles by Kim, E. S.
Right arrow Articles by Kim, Y. S.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kim, E. S.
Right arrow Articles by Kim, Y. S.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, June 2009, p. 2643-2645, Vol. 53, No. 6
0066-4804/09/$08.00+0     doi:10.1128/AAC.01534-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Prevalence of aac(6')-Ib-cr Encoding a Ciprofloxacin-Modifying Enzyme among Enterobacteriaceae Blood Isolates in Korea{triangledown}

Eun Sil Kim,1 Jin-Yong Jeong,1 Jae-Bum Jun,1 Sang-Ho Choi,1 Sang-Oh Lee,1 Mi-Na Kim,2 Jun Hee Woo,1 and Yang Soo Kim1*

Division of Infectious Diseases, Asan Medical Center and Asan Institute for Life Sciences, University of Ulsan College of Medicine, and Center for Antimicrobial Resistance and Microbial Genetics, University of Ulsan,1 Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea2

Received 18 November 2008/ Returned for modification 27 February 2009/ Accepted 6 March 2009

The aac(6')-Ib gene was detected in 86 of 555 (15.5%) Enterobacteriaceae isolates. Among these 86 aac(6')-Ib-positive isolates, 19 (22.0%) were positive for aac(6')-Ib-cr: 4 of 31 (12.9%) Enterobacter spp., 7 of 13 (53.8%) Escherichia coli isolates, and 8 of 42 (19.0%) Klebsiella pneumoniae isolates. There was a strong association between aac(6')-Ib-cr and OXA-1 and CTX-M-1 group β-lactamase genes. One aac(6')-Ib-positive K. pneumoniae isolate carried both aac(6')-Ib-cr and qnrS.

* Corresponding author. Mailing address: Division of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea. Phone: 82-2-3010-3303. Fax: 82-2-3010-6970. E-mail: yskim{at}amc.seoul.kr

{triangledown} Published ahead of print on 16 March 2009.

Antimicrobial Agents and Chemotherapy, June 2009, p. 2643-2645, Vol. 53, No. 6
0066-4804/09/$08.00+0     doi:10.1128/AAC.01534-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»