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Antimicrobial Agents and Chemotherapy, August 2009, p. 3579-3581, Vol. 53, No. 8
0066-4804/09/$08.00+0     doi:10.1128/AAC.00072-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

GES-11, a Novel Integron-Associated GES Variant in Acinetobacter baumannii{triangledown}

Carole Moubareck,1 Sylvie Brémont,1 Marie-Christine Conroy,2 Patrice Courvalin,1* and Thierry Lambert1

Institut Pasteur, Unité des Agents Antibactériens, Centre National de Référence de la Résistance aux Antibiotiques, 75724 Paris Cedex 15,1 Laboratoire de Bactériologie, CHU, 54035 Nancy Cedex, France2

Received 19 January 2009/ Returned for modification 1 March 2009/ Accepted 9 May 2009

New extended-spectrum β-lactamase GES-11 was detected in Acinetobacter baumannii BM4674. The enzyme conferred resistance to β-lactams, including aztreonam, and reduced susceptibility to carbapenems. The structural gene was part of a class 1 integron borne by self-transferable plasmid pIP847. GES-type β-lactamases have not been reported previously in A. baumannii.

* Corresponding author. Mailing address: Institut Pasteur, Unité des Agents Antibactériens, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France. Phone: (33) (1) 45 68 83 20. Fax: (33) (1) 45 68 83 19. E-mail: patrice.courvalin{at}pasteur.fr

{triangledown} Published ahead of print on 18 May 2009.

Antimicrobial Agents and Chemotherapy, August 2009, p. 3579-3581, Vol. 53, No. 8
0066-4804/09/$08.00+0     doi:10.1128/AAC.00072-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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