This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Google Scholar
Right arrow Articles by Álvarez, A.
Right arrow Articles by Reinosa, E.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Álvarez, A.
Right arrow Articles by Reinosa, E.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, September 2009, p. 4022-4024, Vol. 53, No. 9
0066-4804/09/$08.00+0     doi:10.1128/AAC.00145-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibility and Mutations Involved in Clarithromycin Resistance in Helicobacter pylori Isolates from Patients in the Western Central Region of Colombia {triangledown}

Adalucy Álvarez,1* José Ignacio Moncayo,1 Jorge Javier Santacruz,1 Mario Santacoloma,2 Luisa Fernanda Corredor,1,{dagger} and Elizabeth Reinosa1

Universidad Tecnológica de Pereira, Centro de Biología Molecular y Biotecnología, Laboratorio de Microbiología y Parasitología, Pereira, Colombia,1 Universidad de Caldas, Departamento Clínico Quirúrgico, Manizales, Colombia2

Received 30 January 2009/ Returned for modification 8 May 2009/ Accepted 14 June 2009

Resistance to metronidazole, clarithromycin, and amoxicillin (amoxicilline) was found in 82, 3.8, and 1.9% of 106 Helicobacter pylori isolates, respectively. No tetracycline-resistant isolates were found. In all of the clarithromycin-resistant isolates, only one point mutation was present, either A2143G or A2142G. Our results indicate that metronidazole should not be included in the empirical treatment of H. pylori infection in this region.

* Corresponding author. Mailing address: Universidad Tecnológica de Pereira, Facultad de Medicina, Laboratorio de Microbiología y Parasitología, Vereda La Julita, Pereira, Colombia. Phone: 057 6 3215393, ext. 15. Fax: 057 6 3215393, ext. 12. E-mail: adalucyalvarez{at}utp.edu.co

{triangledown} Published ahead of print on 22 June 2009.

{dagger} Present address: Fundación Universitaria del Área Andina, Carrera 24 No. 8-55, Pereira, Colombia.

Antimicrobial Agents and Chemotherapy, September 2009, p. 4022-4024, Vol. 53, No. 9
0066-4804/09/$08.00+0     doi:10.1128/AAC.00145-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»