AAC Accepts, published online ahead of print on 2 July 2007

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Antimicrob. Agents Chemother. doi:10.1128/AAC.00358-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Tick Acquisition of Ehrlichia canis from Dogs Treated with Doxycycline Hyclate

John J. Schaefer, Glen R. Needham, William G. Bremer, Yasuko Rikihisa, S. A. Ewing, and R. W. Stich^*

Departments of Veterinary Preventive Medicine, Entomology and Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210, USA; Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, Oklahoma 74078, USA; Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, 65211, USA

^* To whom correspondence should be addressed. Email: stichrw{at}missouri.edu.

Doxycycline generally alleviates clinical monocytic ehrlichiosis, but its efficacy for control of monocytotropic ehrlichial pathogens requires further investigation. In this study E. canis was detected in dogs treated with doxycycline for 14 days and in ticks fed on these dogs, suggesting that treated dogs can remain reservoirs for E. canis.