|
|
TABLE 2.
Inactivation of HIV-1 by treatment with C31G and SDS
|
|
| Microbicide and concn
(%) during treatment or cell |
% Cells expressing  -gal
genea |
No. of cells counted |
|
| C31G
|
5 × 10 2
(toxic) |
0, 0 |
>5 × 104 |
| 2.5 × 102 |
0, 0 |
>5 × 104 |
| 1.25 × 102 |
0, 0 |
>5 × 104 |
| 6.25 × 103 |
19 ± 6.1, 19 ± 6.4 |
1,080, 805 |
| 2.5 × 103 |
22 ± 7.4, 29 ± 8.1 |
1,620, 1,820 |
| SDS
|
| 5 × 102 |
0, 0 |
>5 × 104
|
| 2.5 × 102 |
0, 0 |
>5 × 104
|
| 1.25 × 102 |
24 ± 3.2, 24 ± 10 |
2,810, 2,190 |
| 6.25 × 103 |
10 ± 1.7, 15 ± 2.1 |
2,390, 2,290 |
| 2.5 × 103 |
9 ± 5.5, 11 ± 3.5 |
1,940,
1,910 |
| Mock infected cells |
0,
0 |
>5 × 104 |
| HIV-1-infected
cells |
17 ± 4.8, 24 ± 5.4 |
2,680, 1,480 |
|
|
a
Data are for duplicate wells. Five
random fields of cells were counted in each plate displaying blue
cells. Duplicate plates were assayed for each sample; individual
numbers are plus or minus the standard deviation within five fields of
one plate.
|
|
