Topoisomerase I Gene Mutations at F270 in the Large Subunit and N184 in the Small Subunit Contribute to the Resistance Mechanism of the Unicellular Parasite Leishmania donovani towards 3,3'-Diindolylmethane
Antimicrob. Agents Chemother. Roy et al.
53: 2589
Supplemental material
Files in this Data Supplement:
- Supplemental file 1
-
Supplemental Figure 1, showing mRNA and protein expression levels in parasites. Supplemental Figure 2, showing sequence alignment of wild-type and mutated topoisomerase I. Supplemental Table 1, listing DIM-resistant mutations in large and small subunits of LdTOPILS.
Zipped PDF document, 337K.
