Crystal Structure of Bacillus anthracis Dihydrofolate Reductase with the Dihydrophthalazine-Based Trimethoprim Derivative RAB1 Provides a Structural Explanation of Potency and Selectivity
Antimicrob. Agents Chemother. Bourne et al.
53: 3065
Supplementary material
Files in this Data Supplement:
- Supplementary file 1
-
Additional methods and Fig. S1 (Electron density for +RAB1 and +TMP at different stages of structure solution), Fig. S2 (Packing interactions discussed for the +RAB1 complex), and Fig. S3 (Comparison of alpha-carbon positional differences and beta-factors of BaDHFR crystallographic structures)
Zipped PDF file, 484K.
