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Antimicrob Agents Chemother. 1980 April; 17(4): 738-739

Ticarcillin concentrations in serum, muscle, and fat after a single intravenous injection.

F D Daschner, G Thoma, H Langmaack and A Dalhoff

ABSTRACT

Ticarcillin concentrations in serum, muscle, and fat were determined simultaneously in 23 patients after the intravenous injection of a single dose of 5 g. The mean concentrations of ticarcillin in serum, muscle, and fat were, respectively, 185 microgram/ml, 18 microgram/g, and 32 microgram/g at 1.0 to 1.5 h after the injections, declining to levels of 11 microgram/ml, 2 microgram/g at 6 to 7 h after the injections. There was no significant difference between the serum tissue ratios at these time periods.

Antimicrob Agents Chemother. 1980 April; 17(4): 738-739






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