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Antimicrob Agents Chemother. 1980 October; 18(4): 642-644

In vitro activity of N-formimidoyl thienamycin (MK0787).

F P Tally, N V Jacobus and S L Gorbach

ABSTRACT

The in vitro activity of N-formimidoyl thienamycin (MK0787), a stable congener of thienamycin, was determined against 200 species of aerobic and 84 species of anaerobic bacteria. The compound was highly active against resistant gram-negative bacilli, penicillin-resistant Staphylococcus aureus, enterococci, and anaerobic bacteria. The new derivative of thienamycin was more active than the parent compound, probably reflecting the stability of the analog.

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Antimicrob Agents Chemother. 1980 October; 18(4): 642-644

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