This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Thonus, I P
Right arrow Articles by Michel, M F
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Thonus, I P
Right arrow Articles by Michel, M F

 Previous Article  |  Next Article 

Antimicrob Agents Chemother. 1982 September; 22(3): 386-390

Ampicillin susceptibility and ampicillin-induced killing rate of Escherichia coli.

I P Thonus, P Fontijne and M F Michel

ABSTRACT

The killing rate induced by ampicillin was determined in 20 strains of Escherichia coli. The apparent generation rate constant for each E. coli showed a characteristic concentration-dependent course. This course can be mathematically described and is determined by four parameters. Three of these parameters determine the speed of the process, and the fourth parameter determines a minimal concentration. The susceptibility of the strains, measured as the minimal inhibitory concentration by an agar dilution method, correlated with the minimal concentration and with a minimal inhibitory concentration calculated from the curve, but not with the rate-determining parameters.

Antimicrob Agents Chemother. 1982 September; 22(3): 386-390




This article has been cited by other articles:

  • Liebscher, M., Jahreis, G., Lucke, C., Grabley, S., Raina, S., Schiene-Fischer, C. (2007). Fatty Acyl Benzamido Antibacterials Based on Inhibition of DnaK-catalyzed Protein Folding. J. Biol. Chem. 282: 4437-4446 [Abstract] [Full Text]  
  • Regoes, R. R., Wiuff, C., Zappala, R. M., Garner, K. N., Baquero, F., Levin, B. R. (2004). Pharmacodynamic Functions: a Multiparameter Approach to the Design of Antibiotic Treatment Regimens. Antimicrob. Agents Chemother. 48: 3670-3676 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»