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Antimicrob Agents Chemother. 1983 February; 23(2): 245-247
Copyright © 1983, American Society for Microbiology. All Rights Reserved.

Synergistic Effect of N-Formimidoyl Thienamycin with Gentamicin and Amikacin Against Streptococcus faecalis

Myles E. Gombert, Leonard B. Berkowitz and Marinella C. Cummings

Division of Infectious Diseases, Department of Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York 11203

ABSTRACT

The in vitro activities of N-formimidoyl thienamycin alone and in combination with amikacin and gentamicin were tested against 10 strains of Streptococcus faecalis. Synergy was demonstrated in 35% of the combinations tested by the microtiter checkerboard technique; 50% were found to be synergistic with time killing curves.

Antimicrob Agents Chemother. 1983 February; 23(2): 245-247
Copyright © 1983, American Society for Microbiology. All Rights Reserved.





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