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Antimicrob Agents Chemother. 1985 June; 27(6): 980-981

Studies with temocillin in a hamster model of antibiotic-associated colitis.

R J Boon and A S Beale

ABSTRACT

Hamsters given the new penicillin temocillin, either orally or by injection, did not develop antibiotic-associated colitis, whereas animals given the control antibiotics cefoxitin or clindamycin developed the disease, which is characterized by marked hemorrhagic cecitis and high cecal levels of Clostridium difficile cytotoxin.


Antimicrob Agents Chemother. 1985 June; 27(6): 980-981




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