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Antimicrob Agents Chemother. 1987 January; 31(1): 104-107

In vitro susceptibility of gram-positive cocci to paldimycin.

D J Pohlod, L D Saravolatz and M M Somerville

ABSTRACT

Paldimycin (U-70138F) is a new antimicrobial agent with activity against gram-positive cocci. Clinical isolates of staphylococci and streptococci were tested. MICs were higher in Mueller-Hinton broth than in nutrient broth. Change in pH had minimal effect on the MICs in either broth. When inoculum size was varied, an inoculum effect was observed. The gram-positive cocci tested were generally more susceptible to paldimycin than to vancomycin.

Antimicrob Agents Chemother. 1987 January; 31(1): 104-107






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