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Antimicrobial Agents and Chemotherapy, Feb 1995, 559-560, Vol 39, No. 2
Copyright © 1995 by the American Society for Microbiology. All rights reserved.

Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations

JM Howell, KA Bresnahan, TO Stair, HS Dhindsa and BA Edwards
Department of Emergency Medicine, Georgetown University Hospital, Washington, D.C., USA.

We studied the effects of closing lacerations with suture or cyanoacrylate tissue adhesive on staphylococcal counts in inoculated guinea pig lacerations. Wounds closed with adhesive alone had lower counts than wounds containing suture material (P < 0.05). The results of a time-kill study were consistent with a bacteriostatic adhesive effect of the adhesive against Staphylococcus aureus.

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