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Antimicrobial Agents and Chemotherapy, Jun 1995, 1265-1268, Vol 39, No. 6
FF Franssen, JT Lumeij and F van Knapen
In the light of the increased incidence of human Encephalitozoon infections
and the absence of an established treatment protocol, a simple in vitro
testing method to compare activities of drugs against Encephalitozoon
cuniculi was developed. With this in vitro method, the 50% inhibitory
concentrations of fumagillin, thiabendazole, albendazole, oxibendazole, and
propamidine isethionate for E. cuniculi in rabbit kidney cells were
determined. Itraconazole, toltrazuril, metronidazole, ronidazole, and
ganciclovir were ineffective in this testing system.
Copyright © 1995 by the American Society for Microbiology. All rights reserved.
Susceptibility of Encephalitozoon cuniculi to several drugs in vitro
Department of Parasitology and Tropical Veterinary Medicine, University of Utrecht, The Netherlands.
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