This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Unal, S.
Right arrow Articles by Akalin, H. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Unal, S.
Right arrow Articles by Akalin, H. E.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, Dec 1996, 2898-2900, Vol 40, No. 12
Copyright © 1996 by the American Society for Microbiology. All rights reserved.

Treatment of enteric fever with pefloxacin for 7 days versus 5 days: a randomized clinical trial

S Unal, M Hayran, S Tuncer, D Gur, O Uzun, M Akova and HE Akalin
Department of Internal Medicine, School of Medicine, Hacettepe University, Ankara, Turkey. su04-k@servis2.net.tr

In this prospective study of enteric fever, 22 patients received 400 mg of pefloxacin twice daily for 5 days (group A) and 24 received 400 mg of pefloxacin twice daily for 7 days (group B). Causative microorganisms were Salmonella typhi (8 in group A, 11 in group B) and Salmonella paratyphi B (14 in group A, 13 in group B). The clinical cure and bacterial eradication rates were 96% (21 of 22) in group A and 100% in group B. In conclusion, 5-day oral administration of pefloxacin was as effective as 7-day treatment of enteric fever caused by Salmonella spp.




Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»