This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Frank, U. Articles by Chambers, H. F. Search for Related Content PubMed PubMed Citation Articles by Frank, U. Articles by Chambers, H. F.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, 05 1996, 1308-1310, Vol 40, No. 5
Copyright © 1996 by the American Society for Microbiology. All rights reserved.

Treatment of Staphylococcus aureus catheter-related infection and infective endocarditis with granulocyte colony-stimulating factor in the experimental rabbit model

U Frank and HF Chambers
San Francisco General Hospital, University of California-San Francisco, USA.

The role of granulocyte colony-stimulating factor with and without antibiotics in the treatment of catheter-related infection and infective endocarditis caused by methicillin-susceptible Staphylococcus aureus was assessed in the experimental rabbit model. Granulocyte colony-stimulating factor stimulated leukocytosis in infected animals but did not increase the clearance of methicillin-susceptible S. aureus from peripheral blood, subcutaneous port catheters, intravascular cardiac catheters, or aortic valve vegetations.

This article has been cited by other articles:

• Siaperas, P., Pefanis, A., Iliopoulos, D., Katsarolis, I., Kyroudi-Voulgari, A., Donta, I., Karayiannakos, P., Giamarellou, H. (2001). Evidence of Less Severe Aortic Valve Destruction after Treatment of Experimental Staphylococcal Endocarditis with Vancomycin and Dexamethasone. Antimicrob. Agents Chemother. 45: 3531-3537 [Abstract] [Full Text]