AAC
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Langaee, T. Y.
Right arrow Articles by Huletsky, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Langaee, T. Y.
Right arrow Articles by Huletsky, A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, December 1998, p. 3296-3300, Vol. 42, No. 12
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

An ampD Gene in Pseudomonas aeruginosa Encodes a Negative Regulator of AmpC beta -Lactamase Expression

Taimour Yousef Langaee, Michèle Dargis, and Ann Huletsky*

Département de biologie médicale, Pavillon Marchand, Université Laval, Ste-Foy, Québec, Canada G1K 7P4

Received 6 April 1998/Returned for modification 28 July 1998/Accepted 23 September 1998

The ampD and ampE genes of Pseudomonas aeruginosa PAO1 were cloned and characterized. These genes are transcribed in the same orientation and form an operon. The deduced polypeptide of P. aeruginosa ampD exhibited more than 60% similarity to the AmpD proteins of enterobacteria and Haemophilus influenzae. The ampD product transcomplemented Escherichia coli ampD mutants to wild-type beta -lactamase expression.

* Corresponding author. Mailing address: Département de biologie médicale, Pavillon Marchand, Université Laval, Ste-Foy, Québec Canada G1K 7P4. Phone: (418) 656-2131, ext. 2669. Fax: (418) 656-7176. E-mail: ann.huletsky{at}rsvs.ulaval.ca.

Antimicrobial Agents and Chemotherapy, December 1998, p. 3296-3300, Vol. 42, No. 12
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Clin. Vaccine Immunol. Clin. Microbiol. Rev.
J. Clin. Microbiol. ALL ASM JOURNALS

Copyright © 1998 by the American Society for Microbiology. All rights reserved.