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Antimicrobial Agents and Chemotherapy, March 1998, p. 698-699, Vol. 42, No. 3
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

In Vitro Activities of Quinupristin-Dalfopristin and the Streptogramin RPR 106972 against Mycoplasma pneumoniae

Koichi Izumikawa,1,* Yoichi Hirakata,1 Toshiyuki Yamaguchi,1 Ryoji Yoshida,2 Hironori Tanaka,2 Hiromu Takemura,3 Shigefumi Maesaki,2 Kazunori Tomono,2 Mitsuo Kaku,3 Kin-Ichi Izumikawa,4 Shimeru Kamihira,1 and Shigeru Kohno2

Department of Laboratory Medicine1 and Second Department of Internal Medicine,2 Nagasaki University School of Medicine, Nagasaki 852, Department of Microbiology, St. Marianna University School of Medicine, Kawasaki 211,3 and Izumikawa Hospital, Nagasaki 859-15,4 Japan

Received 4 August 1997/Returned for modification 22 October 1997/Accepted 15 December 1997

The in vitro activities of quinupristin-dalfopristin and streptogramin RPR 106972 were determined with 44 strains of Mycoplasma pneumoniae and compared to those of macrolides, minocycline, and quinolones. All isolates tested were highly susceptible to macrolides and to quinupristin-dalfopristin (MIC at which 90% of the isolates are inhibited [MIC90], 0.0625 µg/ml), followed by RPR 106972 (MIC90, 0.5 µg/ml), quinolones, and minocycline.


* Corresponding author. Mailing address: Department of Laboratory Medicine, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852, Japan. Phone: 81 (95)-849-7420. Fax: 81 (95)-849-7422. E-mail: peaton-ngs{at}umin.u-tokyo.ac.jp.


Antimicrobial Agents and Chemotherapy, March 1998, p. 698-699, Vol. 42, No. 3
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.



This article has been cited by other articles:

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