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Antimicrobial Agents and Chemotherapy, May 1998, p. 1290-1292, Vol. 42, No. 5
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Susceptibilities of Neonatal Respiratory Isolates of Ureaplasma urealyticum to Antimicrobial Agents

Anne Matlow,1,2,* Cecilia Th'ng,3 Danuta Kovach,1 Patricia Quinn,1,2,4 Michael Dunn,4 and Elaine Wang5,6

Departments of Pediatric Laboratory Medicine1 and Pediatrics,5 The Hospital for Sick Children, Departments of Laboratory Medicine and Pathobiology2 and Pediatrics,6 and Department of Neonatology, Women's College Hospital,4 University of Toronto, and Mycoplasma Laboratory, Ministry of Health Laboratory Services Branch,3 Toronto, Ontario, Canada

Received 4 August 1997/Returned for modification 30 November 1997/Accepted 17 February 1998

Twenty-one neonatal respiratory isolates of Ureaplasma urealyticum were serotyped, and their susceptibilities to ciprofloxacin, gentamicin, chloramphenicol, erythromycin, azithromycin, and doxycycline were tested. Most patient strains were Ureaplasma urealyticum bv. parvum. Chloramphenicol, doxycycline, and azithromycin had the lowest MICs. This data may be useful when designing prophylactic or therapeutic trials of antibiotics for chronic lung disease of the newborn.

* Corresponding author. Mailing address: Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario M5G 1X8, Canada. Phone: (416) 813-5996. Fax: (416) 813-5032. E-mail: anne.matlow{at}mailhub.sickkids.on.ca.

Antimicrobial Agents and Chemotherapy, May 1998, p. 1290-1292, Vol. 42, No. 5
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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