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Antimicrobial Agents and Chemotherapy, November 1999, p. 2790-2792, Vol. 43, No. 11
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

In Vitro Susceptibilities of Neisseria gonorrhoeae to Fatty Acids and Monoglycerides

Gudmundur Bergsson,1,* Ólafur Steingrímsson,2 and Halldor Thormar1

Institute of Biology, University of Iceland,1 and Department of Microbiology, National University Hospital,2 Reykjavik, Iceland

Received 19 January 1999/Returned for modification 3 May 1999/Accepted 28 August 1999

The susceptibility of Neisseria gonorrhoeae to several medium-chain fatty acids and their 1-monoglycerides was tested at a short inactivation time of 1 min. The results indicate that monocaprin, a monoglyceride of capric acid (10 carbon atoms, no double bonds), causes the fastest and most effective killing of all strains of N. gonorrhoeae tested.


* Corresponding author. Mailing address: Institute of Biology, University of Iceland, Grensasvegur 12, 108 Reykjavik, Iceland. Phone: 354-525 4602. Fax: 354-525 4069. E-mail: gudmunb{at}rhi.hi.is.


Antimicrobial Agents and Chemotherapy, November 1999, p. 2790-2792, Vol. 43, No. 11
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.



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