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Antimicrobial Agents and Chemotherapy, April 1999, p. 960-962, Vol. 43, No. 4
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Integron-Mediated Rifampin Resistance in Pseudomonas aeruginosa

Chanwit Tribuddharat and Michael Fennewald*

Department of Microbiology and Immunology, Finch University of the Health Sciences/ The Chicago Medical School, North Chicago, Illinois 60064

Received 20 October 1998/Returned for modification 6 January 1999/Accepted 29 January 1999

A new rifampin resistance gene, arr-2, has been found in Pseudomonas aeruginosa. The ARR-2 protein shows 54% amino acid identity to the rifampin ADP-ribosylating transferase encoded by the arr gene from Mycobacterium smegmatis. This arr-2 gene is located on a gene cassette within a class I integron.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Finch University of the Health Sciences/The Chicago Medical School, North Chicago, IL 60064. Phone: (847) 578-8654. Fax: (847) 578-3349. E-mail: fennewarm{at}mis.finchcms.edu.

Antimicrobial Agents and Chemotherapy, April 1999, p. 960-962, Vol. 43, No. 4
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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