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Antimicrobial Agents and Chemotherapy, September 1999, p. 2314-2316, Vol. 43, No. 9
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Bactericidal/Permeability-Increasing Protein Inhibits Growth of a Strain of Acholeplasma laidlawii and L Forms of the Gram-Positive Bacteria Staphylococcus aureus and Streptococcus pyogenes

Arnold H. Horwitz,* Robert E. Williams, Pei-Syan Liu, and Rossana Nadell

XOMA (U.S.) LLC, Santa Monica, California 90404

Received 28 May 1999/Returned for modification 7 June 1999/Accepted 29 June 1999

Bactericidal/permeability-increasing protein (BPI) inhibited growth of cell wall-deficient Acholeplasma laidlawii and L forms of certain strains of Staphylococcus aureus and Streptococcus pyogenes. However, the same strains of S. aureus and S. pyogenes with intact cell walls were not susceptible to the growth-inhibitory effects of BPI.

* Corresponding author. Mailing address: XOMA (U.S.) LLC, 1545 17th St., Santa Monica, CA 90404. Phone: (310) 829-7681. Fax: (310) 828-2463. E-mail: horwitz{at}xoma.com.

Antimicrobial Agents and Chemotherapy, September 1999, p. 2314-2316, Vol. 43, No. 9
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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  • Levy, O. (2000). Antimicrobial proteins and peptides of blood: templates for novel antimicrobial agents. Blood 96: 2664-2672 [Abstract] [Full Text]  


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