This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Keyes, K.
Right arrow Articles by Lee, M. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Keyes, K.
Right arrow Articles by Lee, M. D.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, February 2000, p. 421-424, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Detection of Florfenicol Resistance Genes in Escherichia coli Isolated from Sick Chickens

Kathleen Keyes,1 Charlene Hudson,2 John J. Maurer,2 Stephan Thayer,2 David G. White,3 and Margie D. Lee1,*

Department of Microbiology and Parasitology1 and Department of Avian Medicine,2 College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, and Center for Veterinary Medicine, Food and Drug Administration, Laurel, Maryland 207083

Received 21 July 1999/Returned for modification 17 September 1999/Accepted 3 November 1999

Florfenicol is an antibiotic approved for veterinary use in cattle in the United States in 1996. Although this drug is not used in poultry, we have detected resistance to florfenicol in clinical isolates of avian Escherichia coli. Molecular typing demonstrated that the florfenicol resistance gene, flo, was independently acquired and is plasmid encoded.

* Corresponding author. Mailing address: Department Medical Microbiology and Parasitology, The University of Georgia, Athens, GA 30602. Phone: (706) 542-5778. Fax: (706) 542-5771. E-mail: leem{at}calc.vet.uga.edu.

Antimicrobial Agents and Chemotherapy, February 2000, p. 421-424, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Liu, M.-C., Wu, C.-M., Liu, Y.-C., Zhao, J.-C., Yang, Y.-L., Shen, J.-Z. (2009). Identification, susceptibility, and detection of integron-gene cassettes of Arcanobacterium pyogenes in bovine endometritis. J DAIRY SCI 92: 3659-3666 [Abstract] [Full Text]  
  • Pallecchi, L., Lucchetti, C., Bartoloni, A., Bartalesi, F., Mantella, A., Gamboa, H., Carattoli, A., Paradisi, F., Rossolini, G. M. (2007). Population Structure and Resistance Genes in Antibiotic-Resistant Bacteria from a Remote Community with Minimal Antibiotic Exposure. Antimicrob. Agents Chemother. 51: 1179-1184 [Abstract] [Full Text]  
  • Kadlec, K., Kehrenberg, C., Schwarz, S. (2007). Efflux-mediated resistance to florfenicol and/or chloramphenicol in Bordetella bronchiseptica: identification of a novel chloramphenicol exporter. J Antimicrob Chemother 59: 191-196 [Abstract] [Full Text]  
  • Sidjabat, H. E., Townsend, K. M., Hanson, N. D., Bell, J. M., Stokes, H. W., Gobius, K. S., Moss, S. M., Trott, D. J. (2006). Identification of blaCMY-7 and associated plasmid-mediated resistance genes in multidrug-resistant Escherichia coli isolated from dogs at a veterinary teaching hospital in Australia. J Antimicrob Chemother 57: 840-848 [Abstract] [Full Text]  
  • Wu, B., Xia, C., Du, X., Cao, X., Shen, J. (2006). Influence of Anti-FloR Antibody on Florfenicol Accumulation in Florfenicol-Resistant Escherichia coli and Enzyme-Linked Immunosorbent Assay for Detection of Florfenicol-Resistant E. coli Isolates. J. Clin. Microbiol. 44: 378-382 [Abstract] [Full Text]  
  • Poole, K. (2005). Efflux-mediated antimicrobial resistance. J Antimicrob Chemother 56: 20-51 [Abstract] [Full Text]  
  • Maynard, C., Bekal, S., Sanschagrin, F., Levesque, R. C., Brousseau, R., Masson, L., Lariviere, S., Harel, J. (2004). Heterogeneity among Virulence and Antimicrobial Resistance Gene Profiles of Extraintestinal Escherichia coli Isolates of Animal and Human Origin. J. Clin. Microbiol. 42: 5444-5452 [Abstract] [Full Text]  
  • Singer, R. S., Patterson, S. K., Meier, A. E., Gibson, J. K., Lee, H. L., Maddox, C. W. (2004). Relationship between Phenotypic and Genotypic Florfenicol Resistance in Escherichia coli. Antimicrob. Agents Chemother. 48: 4047-4049 [Abstract] [Full Text]  
  • Bywater, R., Deluyker, H., Deroover, E., de Jong, A., Marion, H., McConville, M., Rowan, T., Shryock, T., Shuster, D., Thomas, V., Valle, M., Walters, J. (2004). A European survey of antimicrobial susceptibility among zoonotic and commensal bacteria isolated from food-producing animals. J Antimicrob Chemother 54: 744-754 [Abstract] [Full Text]  
  • Blickwede, M., Schwarz, S. (2004). Molecular analysis of florfenicol-resistant Escherichia coli isolates from pigs. J Antimicrob Chemother 53: 58-64 [Abstract] [Full Text]  
  • Maynard, C., Fairbrother, J. M., Bekal, S., Sanschagrin, F., Levesque, R. C., Brousseau, R., Masson, L., Lariviere, S., Harel, J. (2003). Antimicrobial Resistance Genes in Enterotoxigenic Escherichia coli O149:K91 Isolates Obtained over a 23-Year Period from Pigs. Antimicrob. Agents Chemother. 47: 3214-3221 [Abstract] [Full Text]  
  • Meunier, D., Baucheron, S., Chaslus-Dancla, E., Martel, J.-L., Cloeckaert, A. (2003). Florfenicol resistance in Salmonella enterica serovar Newport mediated by a plasmid related to R55 from Klebsiella pneumoniae. J Antimicrob Chemother 51: 1007-1009 [Abstract] [Full Text]  
  • Sanchez, S., McCrackin Stevenson, M. A., Hudson, C. R., Maier, M., Buffington, T., Dam, Q., Maurer, J. J. (2002). Characterization of Multidrug-Resistant Escherichia coli Isolates Associated with Nosocomial Infections in Dogs. J. Clin. Microbiol. 40: 3586-3595 [Abstract] [Full Text]  
  • Bischoff, K. M., White, D. G., McDermott, P. F., Zhao, S., Gaines, S., Maurer, J. J., Nisbet, D. J. (2002). Characterization of Chloramphenicol Resistance in Beta-Hemolytic Escherichia coli Associated with Diarrhea in Neonatal Swine. J. Clin. Microbiol. 40: 389-394 [Abstract] [Full Text]  
  • Doublet, B., Schwarz, S., Nu{beta}beck, E., Baucheron, S., Martel, J.-L., Chaslus-Dancla, E., Cloeckaert, A. (2002). Molecular analysis of chromosomally florfenicol-resistant Escherichia coli isolates from France and Germany. J Antimicrob Chemother 49: 49-54 [Abstract] [Full Text]  
  • Cloeckaert, A., Baucheron, S., Chaslus-Dancla, E. (2001). Nonenzymatic Chloramphenicol Resistance Mediated by IncC Plasmid R55 Is Encoded by a floR Gene Variant. Antimicrob. Agents Chemother. 45: 2381-2382 [Abstract] [Full Text]  
  • White, D. G., Hudson, C., Maurer, J. J., Ayers, S., Zhao, S., Lee, M. D., Bolton, L., Foley, T., Sherwood, J. (2000). Characterization of Chloramphenicol and Florfenicol Resistance in Escherichia coli Associated with Bovine Diarrhea. J. Clin. Microbiol. 38: 4593-4598 [Abstract] [Full Text]  
  • Cloeckaert, A., Baucheron, S., Flaujac, G., Schwarz, S., Kehrenberg, C., Martel, J.-L., Chaslus-Dancla, E. (2000). Plasmid-Mediated Florfenicol Resistance Encoded by the floR Gene in Escherichia coli Isolated from Cattle. Antimicrob. Agents Chemother. 44: 2858-2860 [Abstract] [Full Text]  
  • Lee, A., Mao, W., Warren, M. S., Mistry, A., Hoshino, K., Okumura, R., Ishida, H., Lomovskaya, O. (2000). Interplay between Efflux Pumps May Provide Either Additive or Multiplicative Effects on Drug Resistance. J. Bacteriol. 182: 3142-3150 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»