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Antimicrobial Agents and Chemotherapy, February 2000, p. 425-427, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Efficacy of the Cyclodextrin Liquid Preparation of Itraconazole in Treatment of Denture Stomatitis: Comparison with Itraconazole Capsules

L. J. Cross,1,* J. Bagg,1 and T. C. Aitchison2

University of Glasgow Dental School, Glasgow G2 3JZ,1 and Department of Statistics, University of Glasgow, Glasgow G12 8QW,2 Scotland

Received 10 August 1999/Returned for modification 16 August 1999/Accepted 3 November 1999

This study investigated the efficacy of a cyclodextrin solution of itraconazole in the treatment of Candida-associated denture stomatitis. It was found that the liquid and capsule preparations of itraconazole were equally effective adjuncts in the treatment of this condition. However, the side effect profile indicates that capsules are the preferred formulation.

* Corresponding author. Mailing address: Level 2, Glasgow Dental Hospital & School NHS Trust, 378 Sauchiehall St., Glasgow G2 3JZ, Scotland. Phone: 44 0141 211 9831. Fax: 44 0141 353 1593. E-mail: L.Cross{at}dental.gla.ac.uk.

Antimicrobial Agents and Chemotherapy, February 2000, p. 425-427, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.




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