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Antimicrobial Agents and Chemotherapy, February 2000, p. 447-449, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

In Vitro Activity of ABT-773, a New Ketolide, against Recent Clinical Isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis

Angela B. Brueggemann, Gary V. Doern,* Holly K. Huynh, Elizabeth M. Wingert, and Paul R. Rhomberg

Medical Microbiology Division, Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa

Received 28 June 1999/Returned for modification 13 October 1999/Accepted 4 November 1999

The in vitro activity of ABT-773 was evaluated against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates. ABT-773 was the most active antimicrobial tested against S. pneumoniae. ABT-773 and azithromycin were equivalent in activity against H. influenzae and M. catarrhalis and more active than either clarithromycin or erythromycin.

* Corresponding author. Mailing address: Medical Microbiology Division, C606 GH, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242. Phone: (319) 356-8616. Fax: (319) 356-4916. E-mail: gary-doern{at}uiowa.edu.

Antimicrobial Agents and Chemotherapy, February 2000, p. 447-449, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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