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Antimicrobial Agents and Chemotherapy, February 2000, p. 467-469, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

In Vitro Activities of Ketoconazole, Econazole, Miconazole, and Melaleuca alternifolia (Tea Tree) Oil against Malassezia Species

K. A. Hammer,1,* C. F. Carson,1 and T. V. Riley1,2

Department of Microbiology, The University of Western Australia,1 and The Western Australian Centre for Pathology and Medical Research,2 Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia

Received 22 July 1999/Returned for modification 4 October 1999/Accepted 16 November 1999

The in vitro activities of ketoconazole, econazole, miconazole, and tea tree oil against 54 Malassezia isolates were determined by agar and broth dilution methods. Ketoconazole was more active than both econazole and miconazole, which showed very similar activities. M. furfur was the least susceptible species. M. sympodialis, M. slooffiae, M. globosa, and M. obtusa showed similar susceptibilities to the four agents.

* Corresponding author. Mailing address: Department of Microbiology, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia. Phone: 61 8 9346 4730. Fax: 61 8 9346 2912. E-mail: khammer{at}cyllene.uwa.edu.au.

Antimicrobial Agents and Chemotherapy, February 2000, p. 467-469, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Rincon, S., Cepero de Garcia, M. C., Espinel-Ingroff, A. (2006). A Modified Christensen's Urea and CLSI Broth Microdilution Method for Testing Susceptibilities of Six Malassezia Species to Voriconazole, Itraconazole, and Ketoconazole.. J. Clin. Microbiol. 44: 3429-3431 [Abstract] [Full Text]  
  • Carson, C. F., Hammer, K. A., Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties. Clin. Microbiol. Rev. 19: 50-62 [Abstract] [Full Text]  
  • Garau, M., Pereiro, M. Jr., del Palacio, A. (2003). In Vitro Susceptibilities of Malassezia Species to a New Triazole, Albaconazole (UR-9825), and Other Antifungal Compounds. Antimicrob. Agents Chemother. 47: 2342-2344 [Abstract] [Full Text]  
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