This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rediske, A. M.
Right arrow Articles by Pitt, W. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rediske, A. M.
Right arrow Articles by Pitt, W. G.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, March 2000, p. 771-772, Vol. 44, No. 3
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Pulsed Ultrasound Enhances the Killing of Escherichia coli Biofilms by Aminoglycoside Antibiotics In Vivo

Andrea M. Rediske,1 Beverly L. Roeder,2 Jared L. Nelson,3 Rachel L. Robison,1 G. Bruce Schaalje,4 Richard A. Robison,1 and William G. Pitt3,*

Department of Microbiology,1 Department of Animal Science,2 Department of Chemical Engineering,3 and Department of Statistics,4 Brigham Young University, Provo, Utah

Received 2 July 1999/Returned for modification 21 September 1999/Accepted 29 November 1999

Escherichia coli biofilms on two polyethylene disks were implanted subcutaneously into rabbits receiving systemic gentamicin. Ultrasound was applied for 24 h to one disk. Both disks were removed, and viable bacteria were counted. Pulsed ultrasound significantly reduced bacterial viability below that of nontreated biofilms without damage to the skin.

* Corresponding author. Mailing address: 350M Clyde Building, Brigham Young University, Provo UT 84602. Phone: (801) 378-2589. Fax: (801) 379-7799. E-mail: pitt{at}byu.edu.

Antimicrobial Agents and Chemotherapy, March 2000, p. 771-772, Vol. 44, No. 3
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Cai, X.-Z., Yan, S.-G., Wu, H.-B., He, R.-X., Dai, X.-S., Chen, H.-X., Yan, R.-J., Zhao, X.-H. (2007). Effect of Delayed Pulsed-Wave Ultrasound on Local Pharmacokinetics and Pharmacodynamics of Vancomycin-Loaded Acrylic Bone Cement In Vivo. Antimicrob. Agents Chemother. 51: 3199-3204 [Abstract] [Full Text]  
  • Hazan, Z., Zumeris, J., Jacob, H., Raskin, H., Kratysh, G., Vishnia, M., Dror, N., Barliya, T., Mandel, M., Lavie, G. (2006). Effective Prevention of Microbial Biofilm Formation on Medical Devices by Low-Energy Surface Acoustic Waves. Antimicrob. Agents Chemother. 50: 4144-4152 [Abstract] [Full Text]  
  • Lewis, K. (2001). Riddle of Biofilm Resistance. Antimicrob. Agents Chemother. 45: 999-1007 [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»