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Antimicrobial Agents and Chemotherapy, May 2000, p. 1367-1369, Vol. 44, No. 5
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

MICs of Oxazolidinones for Rhodococcus equi Strains Isolated from Humans and Animals

Terry L. Bowersock,1,* Sarah A. Salmon,1 Ellen S. Portis,1 John F. Prescott,2 Denise A. Robison,3 Charles W. Ford,4 and Jeffrey L. Watts1

Animal Health Therapeutics Research,1 and Infectious Diseases Research,4 Pharmacia & Upjohn, Kalamazoo, Michigan 49001; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada N1G 2W12; and University Hospitals, Oklahoma City, Oklahoma 731263

Received 1 November 1999/Returned for modification 6 December 1999/Accepted 27 January 2000

Eperezolid and linezolid are representatives of a new class of orally active, synthetic antimicrobial agents. The in vitro activity values (MICs) of linezolid, eperezolid, and comparator antibiotics against 102 strains of Rhodococcus equi isolated from humans and animals were determined. Linezolid was more active than eperezolid against the strains tested; premafloxacin was the most active comparator antibiotic.

* Corresponding author. Mailing address: Animal Health Therapeutics Research, Pharmacia & Upjohn, 7923-190-353, Kalamazoo, MI 49001-0199. Phone: (616) 833-2614. Fax: (616) 833-2855. E-mail: Terry.L.Bowersock{at}am.pnu.com.

Antimicrobial Agents and Chemotherapy, May 2000, p. 1367-1369, Vol. 44, No. 5
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Jacks, S. S., Giguere, S., Nguyen, A. (2003). In Vitro Susceptibilities of Rhodococcus equi and Other Common Equine Pathogens to Azithromycin, Clarithromycin, and 20 Other Antimicrobials. Antimicrob. Agents Chemother. 47: 1742-1745 [Abstract] [Full Text]  
  • Vera-Cabrera, L., Gomez-Flores, A., Escalante-Fuentes, W. G., Welsh, O. (2001). In Vitro Activity of PNU-100766 (Linezolid), a New Oxazolidinone Antimicrobial, against Nocardia brasiliensis. Antimicrob. Agents Chemother. 45: 3629-3630 [Abstract] [Full Text]  
  • Brown-Elliott, B. A., Ward, S. C., Crist, C. J., Mann, L. B., Wilson, R. W., Wallace, R. J. Jr. (2001). In Vitro Activities of Linezolid against Multiple Nocardia Species. Antimicrob. Agents Chemother. 45: 1295-1297 [Abstract] [Full Text]  


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