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Antimicrobial Agents and Chemotherapy, January 2001, p. 359-362, Vol. 45, No. 1
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.1.359-362.2001

In Vitro Antibiotic Susceptibility of Neisseria gonorrhoeae in Jakarta, Indonesia

Murad Lesmana,1 Carlos I. Lebron,1 Djufri Taslim,2 Periska Tjaniadi,1 Decy Subekti,1 Momtaz O. Wasfy,3 James R. Campbell,1 and Buhari A. Oyofo1,*

U.S. Naval Medical Research Unit No. 2, Jakarta,1 and Municipal Health Services, North Jakarta,2 Indonesia, and U.S. Naval Medical Research Unit No. 3, Cairo, Egypt3

Received 22 May 2000/Returned for modification 26 August 2000/Accepted 17 October 2000

Antibiotic susceptibilities were determined for 122 Neisseria gonorrheae isolates obtained from 400 sex workers in Jakarta, Indonesia, and susceptibilities to ciprofloxacin, cefuroxime, cefoxitin, cefotaxime, ceftriaxone, chloramphenicol, and spectinomycin were found. All isolates were resistant to tetracycline. A number of the isolates demonstrated decreased susceptibilities to erythromycin (MIC >=  1.0 µg/ml), thiamphenicol (MIC >=  1.0 µg/ml), kanamycin (MIC >=  16.0 µg/ml), penicillin (MIC >=  2.0 µg/ml), gentamicin (MIC >=  16.0 µg/ml), and norfloxacin (MIC = 0.5 µg/ml). These data showed that certain antibiotics previously used in the treatment of gonorrhea are no longer effective.

* Corresponding author. Mailing address: Commanding Officer, U.S. Naval Medical Research Unit No. 2, Unit 8132, Box 3, FPO, New York, AP 96520-8132. Phone: 6221-4457/58. Fax: 011-6221-424-4507. E-mail: oyofo{at}namru2.org.

Antimicrobial Agents and Chemotherapy, January 2001, p. 359-362, Vol. 45, No. 1
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.1.359-362.2001


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