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Antimicrobial Agents and Chemotherapy, October 2001, p. 2931-2932, Vol. 45, No. 10
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.10.2931-2932.2001

Variation within the vat(E) Allele of Enterococcus faecium Isolates from Retail Poultry Samples

S. Simjee,^* P. F. McDermott, D. D. Wagner, and D. G. White

Division of Animal and Food Microbiology, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, Maryland

Received 12 March 2001/Returned for modification 8 May 2001/Accepted 16 July 2001

In a survey of retail meat samples, twelve quinupristin-dalfopristin-resistant (MICs, 4 mg/liter) Enterococcus faecium isolates that carried a vat(E) gene were recovered. DNA sequence comparison revealed five new variations in the vat(E) allele among 12 isolates, which were designated vat(E-4) through vat(E-8); two isolates had vat(E-1). There was no correlation between the number of base changes and the quinupristin-dalfopristin MIC.

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^* Corresponding author. Mailing address: Office of Research, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD 20708. Phone: (301) 827-8046. Fax: (301) 827-8250. E-mail: ssimjee{at}cvm.fda.gov.

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Antimicrobial Agents and Chemotherapy, October 2001, p. 2931-2932, Vol. 45, No. 10
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.10.2931-2932.2001

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