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Antimicrobial Agents and Chemotherapy, October 2001, p. 2961-2964, Vol. 45, No. 10
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.10.2961-2964.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Novel Gene Cassettes and Integrons

E. D. J. Peters, M. A. Leverstein-van Hall, A. T. A. Box, J. Verhoef, and A. C. Fluit*

Eijkman-Winkler Institute, University Medical Center Utrecht, Utrecht, The Netherlands

Received 18 December 2000/Returned for modification 27 April 2001/Accepted 25 June 2001

An increase in multiresistant Enterobacteriaceae was observed at one of the departments of the University Medical Center Utrecht. Nine different integrons and 17 gene cassettes were found, including the new gene cassette aadA8. This cassette was highly related to aadA3 and aadA2. In addition, an unknown promoter sequence was found for two integrons.

* Corresponding author. Mailing address; Eijkman-Winkler Institute, University Medical Center Utrecht, Room G04.614, P.O. Box 85500, 3508 GA Utrecht, The Netherlands. Phone: 31302507630. Fax: 31302541770. E-mail: A.C.Fluit{at}lab.azu.nl.

Antimicrobial Agents and Chemotherapy, October 2001, p. 2961-2964, Vol. 45, No. 10
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.10.2961-2964.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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