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Antimicrobial Agents and Chemotherapy, June 2001, p. 1889-1891, Vol. 45, No. 6
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.6.1889-1891.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Mechanisms of Macrolide Resistance in Clinical Group B Streptococci Isolated in France

Frederic Fitoussi,1 Chawki Loukil,1 Isabelle Gros,2 Olivier Clermont,1 Patricia Mariani,1 Stephane Bonacorsi,1 Isabelle Le Thomas,1 Dominique Deforche,1 and Edouard Bingen1,*

Service de Microbiologie, Hôpital Robert Debré, 75019 Paris,1 and Service de Microbiologie Hôpital Delafontaine, 93200 Saint Denis,2 France

Received 12 January 2001/Returned for modification 19 February 2001/Accepted 17 March 2001

Macrolide susceptibility was investigated in clinical group B streptococci obtained from neonates or pregnant women in 2000 in France. Of 490 consecutive isolates, 18% were resistant to erythromycin. The erm(B), erm(A) subclass erm(TR), and mef(A) genes were harbored by 47, 45, and 6% of these strains, respectively. Two isolates did not harbor erm or mef genes.


* Corresponding author. Mailing address: Service de Microbiologie, Hôpital R. Debré, 48 Bd Sérurier, 75019 Paris, France. Phone: 33 (1) 40 03 23 40. Fax: 33 (1) 40 03 24 50. E-mail: edouard.bingen{at}rdb.ap-hop-paris.fr.


Antimicrobial Agents and Chemotherapy, June 2001, p. 1889-1891, Vol. 45, No. 6
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.6.1889-1891.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.



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