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Antimicrobial Agents and Chemotherapy, June 2001, p. 1894-1895, Vol. 45, No. 6
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.6.1894-1895.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Effects of Synthetic Cecropin Analogs on in Vitro Growth of Acholeplasma laidlawii†

Wayne B. Borth,1,* V. P. Jones,2 D. E. Ullman,3 and J. S. Hu1

University of Hawaii, Department of Plant and Environmental Protection Sciences, Honolulu, Hawaii 968221; Washington State University, Tree Fruit Research and Extension Center, Wenatchee, Washington 988012; and University of California, Department of Entomology, Davis, California 956163

Received 24 July 2000/Returned for modification 11 January 2001/Accepted 5 March 2001

Four synthetic peptides (Peptidyl MIMs; Demeter Biotechnologies, Inc.) were evaluated for their in vitro activity against Acholeplasma laidlawii. Fifty percent effective concentration values ranged from 1 to 15 µM. Three of these compounds are more lethal than cecropin B against A. laidlawii.

* Corresponding author. Mailing address: University of Hawaii, Department of Plant and Environmental Protection Sciences, 3190 Maile Way, Honolulu, HI 96822. Phone: (808) 956-2830. Fax: (808) 956-2832. E-mail: borth{at}hawaii.edu.

dagger Journal series 4548 of the College of Tropical Agriculture and Human Resources.

Antimicrobial Agents and Chemotherapy, June 2001, p. 1894-1895, Vol. 45, No. 6
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.6.1894-1895.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.




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