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Antimicrobial Agents and Chemotherapy, January 2002, p. 255-258, Vol. 46, No. 1
0066-4804/01/$04.00+0     DOI: 10.1128/AAC.46.1.255-258.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Nosocomial Outbreak of Carbapenem-Resistant Pseudomonas aeruginosa with a New blaIMP Allele, blaIMP-7

Alan Patrick Gibb,1* Chanwit Tribuddharat,1 Richard A. Moore,1 Thomas J. Louie,1 Wally Krulicki,1 David M. Livermore,2 Marie-France I. Palepou,2 and Neil Woodford2

Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada T2N 4N1,1 Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT, United Kingdom2

Received 5 March 2001/ Returned for modification 14 July 2001/ Accepted 27 September 2001

Pseudomonas aeruginosa isolates from an outbreak in Canada were highly resistant to carbapenems and ceftazidime but not piperacillin. They produced a novel integron-associated metallo-ß-lactamase, designated IMP-7, with 91% identity to IMP-1. blaIMP-7 was not detected with standard blaIMP-specific primers, owing to mismatches in the forward primer.

* Corresponding author. Present address: Medical School, Teviot Place, Edinburgh EH8 9AG, Scotland, United Kingdom. Phone: 44-131 536 6902. Fax: 44-131 650 6515. E-mail: a.p.gibb{at}ed.ac.uk.

Antimicrobial Agents and Chemotherapy, January 2002, p. 255-258, Vol. 46, No. 1
0066-4804/01/$04.00+0     DOI: 10.1128/AAC.46.1.255-258.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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