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Antimicrobial Agents and Chemotherapy, November 2002, p. 3641-3643, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3641-3643.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Antimicrobial Resistance in Haemophilus influenzae Isolated during Population-Based Surveillance for Meningitis in Salvador, Brazil

Joice Neves Reis,1,2 Josilene Borges Lima,1 Guilherme Souza Ribeiro,1 Soraia Machado Corderio,1 Kátia Salgado,3 Mitermayer Galvão Reis,1 and Albert I. Ko1,4*

Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde,1 Faculdade de Farmácia, Universidade Federal da Bahia,2 Hospital Couto Maia, Secretaria da Saúde do Estado da Bahia, Salvador, Brazil,3 Division of International Medicine and Infectious Diseases, Department of Medicine, Weill Medical College of Cornell University, New York, New York 100214

Received 4 June 2002/ Returned for modification 16 July 2002/ Accepted 5 August 2002

Antimicrobial susceptibility was determined for 150 Haemophilus influenzae isolates obtained during population-based surveillance for meningitis in Salvador, Brazil. Ten (6.7%) isolates were resistant to ampicillin and chloramphenicol. Of these, two isolates, a ß-lactamase and non-ß-lactamase producer, were resistant to amoxacillin-clavulinic acid. These findings indicate that present antibiotic regimens in Brazil may not be appropriate for the treatment of H. influenzae meningitis.

* Corresponding author. Mailing address: Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz/MS, Rua Waldemar Falcão, 121, Salvador, Bahia 40295-001, Brazil. Phone: (55 71) 356-4320. Fax: (55 71) 356-2155. E-mail: aik2001{at}med.cornell.edu.

Antimicrobial Agents and Chemotherapy, November 2002, p. 3641-3643, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3641-3643.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Bajanca, P., Canica, M. (2004). Emergence of Nonencapsulated and Encapsulated Non-b-Type Invasive Haemophilus influenzae Isolates in Portugal (1989-2001). J. Clin. Microbiol. 42: 807-810 [Abstract] [Full Text]  


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