This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Giamarellos-Bourboulis, E. J.
Right arrow Articles by Giamarellou, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Giamarellos-Bourboulis, E. J.
Right arrow Articles by Giamarellou, H.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, December 2002, p. 3997-3999, Vol. 46, No. 12
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.12.3997-3999.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

In Vitro Killing Effect of Moxifloxacin on Clinical Isolates of Stenotrophomonas maltophilia Resistant to Trimethoprim-Sulfamethoxazole

Evangelos J. Giamarellos-Bourboulis, Lazaros Karnesis, Irene Galani, and Helen Giamarellou*

4th Department of Internal Medicine, Medical School, University of Athens, Athens, Greece

Received 14 May 2002/ Returned for modification 14 June 2002/ Accepted 19 August 2002

The time-kill effect of moxifloxacin on 20 genetically distinct isolates of Stenotrophomonas maltophilia resistant to trimethoprim-sulfamethoxazole was studied. The majority (80%) were killed by a concentration equivalent to four times the MIC; the MIC induced a transient decrease in bacterial counts at 4 h, followed by regrowth. No effect was detected in four isolates. These results merit further clinical consideration.

* Corresponding author. Mailing address: 4th Department of Internal Medicine, Sismanoglion General Hospital, 1 Sismanogliou St., 151 26 Maroussi Attikis, Greece. Phone: (3010) 80 39 542. Fax: (3010) 80 39 543. E-mail: giamarel{at} internet.gr.

Antimicrobial Agents and Chemotherapy, December 2002, p. 3997-3999, Vol. 46, No. 12
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.12.3997-3999.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»