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Antimicrobial Agents and Chemotherapy, October 2003, p. 3321-3322, Vol. 47, No. 10
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.10.3321-3322.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Virucidal Efficacy of Soap and Water against Human Immunodeficiency Virus in Genital Secretions

Jonathan Z. Li, Elizabeth C. Mack, and Jay A. Levy*

Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, California

Received 10 April 2003/ Returned for modification 18 June 2003/ Accepted 22 July 2003

A common bar soap and tap water solution was able to demonstrate a 30-fold human immunodeficiency virus (HIV) inactivation and a 57 to 87% reduction in viable peripheral blood mononuclear cells in a mixture of cervicovaginal lavage fluid and seminal fluid. These observations indicate that soap and water might be used to inactivate HIV and HIV-infected cells in genital secretions.

* Corresponding author. Mailing address: 513 Parnassus Ave., S1280, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143-1270. Phone: (415) 476-4071. Fax: (415) 476-8365. E-mail: jalevy{at}itsa.ucsf.edu.

Antimicrobial Agents and Chemotherapy, October 2003, p. 3321-3322, Vol. 47, No. 10
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.10.3321-3322.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.





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