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Antimicrobial Agents and Chemotherapy, August 2003, p. 2703-2705, Vol. 47, No. 8
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.8.2703-2705.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of Florfenicol against Bovine and Porcine Respiratory Tract Pathogens

Saskia Priebe and Stefan Schwarz*

Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), 31535 Neustadt-Mariensee, Germany

Received 15 April 2003/ Returned for modification 2 May 2003/ Accepted 12 May 2003

Florfenicol in vitro activities for a total of 756 bacterial isolates from respiratory tract infections of cattle and swine were comparatively investigated by the agar diffusion method and the microdilution broth method. Florfenicol showed high in vitro activity against Pasteurella multocida, Mannheimia haemolytica, Actinobacillus pleuropneumoniae, and Streptococcus suis, with all of the isolates inhibited by <=2 µg of florfenicol per ml.

* Corresponding author. Mailing address: Institut für Tierzucht der Bundesforschungsanstalt für Landwirtschaft (FAL), Höltystr. 10, 31535 Neustadt-Mariensee, Germany. Phone: 49-5034-871-241. Fax: 49-5034-871-246. E-mail: stefan.schwarz{at}fal.de.

Antimicrobial Agents and Chemotherapy, August 2003, p. 2703-2705, Vol. 47, No. 8
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.8.2703-2705.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kadlec, K., Kehrenberg, C., Schwarz, S. (2007). Efflux-mediated resistance to florfenicol and/or chloramphenicol in Bordetella bronchiseptica: identification of a novel chloramphenicol exporter. J Antimicrob Chemother 59: 191-196 [Abstract] [Full Text]  
  • Kehrenberg, C., Schwarz, S. (2006). Distribution of Florfenicol Resistance Genes fexA and cfr among Chloramphenicol-Resistant Staphylococcus Isolates.. Antimicrob. Agents Chemother. 50: 1156-1163 [Abstract] [Full Text]  
  • Kehrenberg, C., Schwarz, S. (2005). Plasmid-borne florfenicol resistance in Pasteurella multocida. J Antimicrob Chemother 55: 773-775 [Abstract] [Full Text]  
  • Kadlec, K., Kehrenberg, C., Wallmann, J., Schwarz, S. (2004). Antimicrobial Susceptibility of Bordetella bronchiseptica Isolates from Porcine Respiratory Tract Infections. Antimicrob. Agents Chemother. 48: 4903-4906 [Abstract] [Full Text]  
  • Kehrenberg, C., Mumme, J., Wallmann, J., Verspohl, J., Tegeler, R., Kuhn, T., Schwarz, S. (2004). Monitoring of florfenicol susceptibility among bovine and porcine respiratory tract pathogens collected in Germany during the years 2002 and 2003. J Antimicrob Chemother 54: 572-574 [Full Text]  
  • Schwarz, S., Kehrenberg, C., Salmon, S. A., Watts, J. L. (2004). In vitro activities of spectinomycin and comparator agents against Pasteurella multocida and Mannheimia haemolytica from respiratory tract infections of cattle. J Antimicrob Chemother 53: 379-382 [Abstract] [Full Text]  
  • Blickwede, M., Schwarz, S. (2004). Molecular analysis of florfenicol-resistant Escherichia coli isolates from pigs. J Antimicrob Chemother 53: 58-64 [Abstract] [Full Text]  


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