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Antimicrobial Agents and Chemotherapy, April 2004, p. 1361-1364, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1361-1364.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Increasing Prevalence of Methicillin-Resistant Staphylococcus aureus Causing Nosocomial Infections at a University Hospital in Taiwan from 1986 to 2001

Po-Ren Hsueh,1,2,3* Lee-Jene Teng,4 Wen-Hwei Chen,3 Huei-Ju Pan,1,3 Mei-Lin Chen,1,3 Shan-Chwen Chang,2,3 Kwen-Tay Luh,1,2 and Fang-Yue Lin3

Departments of Laboratory Medicine,1 Internal Medicine,2 Committee of Infection Control, National Taiwan University Hospital,3 School of Medical Technology, National Taiwan University College of Medicine, Taipei, Taiwan4

Received 3 June 2003/ Returned for modification 1 September 2003/ Accepted 30 December 2003

A rapid emergence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection (from 26.3% in 1986 to 77% in 2001) was found. The susceptibility of 200 nonduplicate blood isolates of MRSA and 100 MRSA isolates causing refractory bacteremia to 22 antimicrobial agents disclosed that glycopeptides, quinupristin-dalfopristin, and linezolid remained the most active agents.

* Corresponding author. Mailing address: Department of Laboratory Medicine, National Taiwan University Hospital, No 7, Chung-Shan South Rd., Taipei, Taiwan. Phone: 886-2-23123456, ext. 5363. Fax: 886-2-23224263. E-mail: hsporen{at}ha.mc.ntu.edu.tw.

Antimicrobial Agents and Chemotherapy, April 2004, p. 1361-1364, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1361-1364.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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