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Antimicrobial Agents and Chemotherapy, April 2004, p. 1410-1412, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1410-1412.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Macrolide Resistance Determinants of Invasive and Noninvasive Group B Streptococci in a Turkish Hospital

Ziya Cibali Acikgoz,1* Ebru Almayanlar,2 Sohret Gamberzade,1 and Safiye Gocer1

Department of Microbiology and Clinical Microbiology, Fatih University Faculty of Medicine, Fatih Üniversitesi Hastanesi, 06510 Emek,1 METIS Biotechnology Ltd., Ostim, Ankara, Turkey2

Received 28 August 2003/ Returned for modification 5 November 2003/ Accepted 16 December 2003

Macrolide resistance in 156 consecutive group B streptococcal isolates was investigated. Thirty-five isolates (22.4%) had inducible (80%) or constitutive (20%) erythromycin resistance. The genes responsible were erm(B), erm(A) subclass erm(TR), and erm(B) plus erm(TR) in 62.9, 2.9, and 8.6% of isolates, respectively. Nine isolates (25.7%) harbored neither mef nor detectable erm genes.

* Corresponding author. Mailing address: Fatih Üniversitesi Hastanesi, Alpaslan Türkes Caddesi, No. 57, 06510 Emek, Ankara, Turkey. Phone: 90 312 2126262. Fax: 90 312 2153614. E-mail: zcacikgoz{at}yahoo.com.

Antimicrobial Agents and Chemotherapy, April 2004, p. 1410-1412, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1410-1412.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Zeng, X., Kong, F., Wang, H., Darbar, A., Gilbert, G. L. (2006). Simultaneous Detection of Nine Antibiotic Resistance-Related Genes in Streptococcus agalactiae Using Multiplex PCR and Reverse Line Blot Hybridization Assay. Antimicrob. Agents Chemother. 50: 204-209 [Abstract] [Full Text]  


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