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Antimicrobial Agents and Chemotherapy, August 2004, p. 3119-3121, Vol. 48, No. 8
0066-4804/04/$08.00+0 DOI: 10.1128/AAC.48.8.3119-3121.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.
Inhibitory Activities of Colicins against Escherichia coli Strains Responsible for Postweaning Diarrhea and Edema Disease in Swine
Chad H. Stahl,1* Todd R. Callaway,2 Leslie M. Lincoln,1 Steven M. Lonergan,1 and Kenneth J. Genovese2
Department of Animal Science, Iowa State University, Ames, Iowa,1
Food and Feed Safety Research Unit, USDA Agricultural Research Service, College Station, Texas2
Received 24 February 2004/
Returned for modification 13 April 2004/
Accepted 26 April 2004
The efficacies of colicins E1 and N against Escherichia coli strains responsible for postweaning diarrhea and edema disease, two of the most prevalent disease problems for pigs in the United States, were determined in vitro. These proteins may provide an environmentally sound means for the prevention of these infections in swine.
* Corresponding author. Mailing address: Iowa State University, Department of Animal Science, 201 Kildee Hall, Ames, Iowa 50011. Phone: (515) 294-5990. Fax: (515) 294-1399. E-mail:
cstahl{at}iastate.edu.
Antimicrobial Agents and Chemotherapy, August 2004, p. 3119-3121, Vol. 48, No. 8
0066-4804/04/$08.00+0 DOI: 10.1128/AAC.48.8.3119-3121.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.
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