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Antimicrobial Agents and Chemotherapy, August 2004, p. 3159-3161, Vol. 48, No. 8
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.8.3159-3161.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

High Prevalence of Extended-Spectrum ß-Lactamase-Producing Strains among Blood Isolates of Enterobacter spp. Collected in a Tertiary Hospital during an 8-Year Period and Their Antimicrobial Susceptibility Patterns

Hyunjoo Pai,1* Jung Yun Hong,2 Jeong-Hum Byeon,1 Yun-Kyung Kim,2 and Hoan-Jong Lee2

Division of Infectious Diseases, Hanyang University College of Medicine,1 Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea2

Received 16 October 2003/ Returned for modification 4 January 2004/ Accepted 21 April 2004

Of 72 blood isolates of Enterobacter spp. collected over an 8-year period, 50% (36 of 72) were derepressed or partially derepressed AmpC mutants. The extended-spectrum ß-lactamase (ESBL) production rate was 43% (31 of 72 isolates), and 67.3% (31 of 46) of extended-spectrum cephalosporin-resistant strains produced ESBLs. Thus, a confirmatory test for ESBL production is necessary for extended-spectrum cephalosporin-resistant Enterobacter spp.

* Corresponding author. Mailing address: Division of Infectious Disease, Department of Internal Medicine, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Korea. Phone: 82-2-2290-8356. Fax: 82-2-2298-9183. E-mail: paihj{at}hanyang.ac.kr.

Antimicrobial Agents and Chemotherapy, August 2004, p. 3159-3161, Vol. 48, No. 8
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.8.3159-3161.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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