This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Boulestin, A.
Right arrow Articles by Izopet, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Boulestin, A.
Right arrow Articles by Izopet, J.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, September 2004, p. 3610-3612, Vol. 48, No. 9
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.9.3610-3612.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Convenient Biological Assay for Polyethylene Glycol-Interferons in Patients with Hepatitis C

Anne Boulestin,1* Nassim Kamar,2 Florence Legrand-Abravanel,1 Karine Sandres-Saune,1 Laurent Alric,3 Jean-Pierre Vinel,4 Lionel Rostaing,2 and Jacques Izopet1

Laboratoire de Virologie EA 2046-IFR 30,1 Service de Médecine Interne,3 Service d'Hépato-Gastro-Entérologie, CHU PURPAN,4 Unité de Transplantation d'Organes, CHU RANGUEIL, Toulouse, France2

Received 9 January 2004/ Returned for modification 18 March 2004/ Accepted 11 May 2004

The vesicular stomatitis virus cytopathic effect reduction assay is suitable to quantify polyethylene glycol-alpha interferon 2a (PEG-IFN-{alpha}2a) and PEG-IFN-{alpha}2b. Human serum and ribavirin did not interfere with the assay. This bioassay was successfully used for assaying PEG-IFN-{alpha}2a and PEG-IFN-{alpha}2b in serum samples from patients undergoing combination therapy.

* Corresponding author. Mailing address: Laboratoire de Virologie EA 2046-IFR 30, CHU PURPAN, Place du Dr Baylac, TSA 40031, 31059 Toulouse Cedex 9, France. Phone: 33 5 61 77 24 63. Fax: 33 5 61 77 25 42. E-mail: aboulestin{at}yahoo.fr.

Antimicrobial Agents and Chemotherapy, September 2004, p. 3610-3612, Vol. 48, No. 9
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.9.3610-3612.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Francois, C., Bernard, I., Castelain, S., Charleston, B., Fray, M. D., Capiod, J.-C., Duverlie, G. (2005). Quantification of Different Human Alpha Interferon Subtypes and Pegylated Interferon Activities by Measuring MxA Promoter Activation. Antimicrob. Agents Chemother. 49: 3770-3775 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»