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Antimicrobial Agents and Chemotherapy, January 2005, p. 414-417, Vol. 49, No. 1
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.1.414-417.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

dfrA20, a Novel Trimethoprim Resistance Gene from Pasteurella multocida

Corinna Kehrenberg and Stefan Schwarz*

Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), Neustadt-Mariensee, Germany

Received 23 April 2004/ Returned for modification 16 July 2004/ Accepted 18 September 2004

A novel trimethoprim resistance gene, designated dfrA20, was detected on the 11-kb plasmid pCCK154 from Pasteurella multocida. The dfrA20 gene codes for a dihydrofolate reductase of 169 amino acids. Sequence comparisons revealed that the DfrA20 protein differed distinctly from all dihydrofolate reductases known so far.

* Corresponding author. Mailing address: Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), Höltystr. 10, 31535 Neustadt-Mariensee, Germany. Phone: 49-5034-871-241. Fax: 49-5034-871-246. E-mail: stefan.schwarz{at}fal.de.

Antimicrobial Agents and Chemotherapy, January 2005, p. 414-417, Vol. 49, No. 1
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.1.414-417.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kehrenberg, C., Catry, B., Haesebrouck, F., de Kruif, A., Schwarz, S. (2005). Novel Spectinomycin/Streptomycin Resistance Gene, aadA14, from Pasteurella multocida. Antimicrob. Agents Chemother. 49: 3046-3049 [Abstract] [Full Text]  
  • Doublet, B., Schwarz, S., Kehrenberg, C., Cloeckaert, A. (2005). Florfenicol Resistance Gene floR Is Part of a Novel Transposon. Antimicrob. Agents Chemother. 49: 2106-2108 [Abstract] [Full Text]  


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