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Antimicrobial Agents and Chemotherapy, December 2005, p. 5136-5138, Vol. 49, No. 12
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.12.5136-5138.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

In Vitro Activity of Ravuconazole against 923 Clinical Isolates of Nondermatophyte Filamentous Fungi

Manuel Cuenca-Estrella,* Alicia Gomez-Lopez, Emilia Mellado, Guillermo Garcia-Effron, Araceli Monzon, and Juan Luis Rodriguez-Tudela

Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain

Received 13 July 2005/ Returned for modification 22 August 2005/ Accepted 12 September 2005

The in vitro activities of ravuconazole against 575 clinical strains of Aspergillus spp. and 348 nondermatophyte non-Aspergillus spp. were analyzed. Ravuconazole was active against Aspergillus spp., other hyaline filamentous fungi, black molds, and some Mucorales. Species such as Scedosporium prolificans, Fusarium spp., and Scopulariopsis spp. were resistant to the triazole.

* Corresponding author. Mailing address: Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra Majadahonda-Pozuelo Km 2, 28220 Majadahonda (Madrid), Spain. Phone: 34-91-5097961. Fax: 34-91-5097966. E-mail: mcuenca-estrella{at}isciii.es.

Antimicrobial Agents and Chemotherapy, December 2005, p. 5136-5138, Vol. 49, No. 12
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.12.5136-5138.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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