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Antimicrobial Agents and Chemotherapy, December 2005, p. 5179-5181, Vol. 49, No. 12
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.12.5179-5181.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Novel Rearrangement of a Class 2 Integron in Two Non-Epidemiologically Related Isolates of Acinetobacter baumannii

María Soledad Ramírez, Cecilia Quiroga, and Daniela Centrón*

Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina

Received 22 April 2005/ Returned for modification 12 July 2005/ Accepted 9 September 2005

Tn7::In2-8 contains sat2-aadB-catB2({Delta}attC)-dfrA1-sat2-aadA1-orfX in the variable region of a class 2 integron embedded in the Tn7-like transposon. This novel transposon was inserted in its preferred site downstream of the glms gene in Acinetobacter baumannii. Acquisition of the pseudocassette catB2 could have arisen by a secondary-site integrase-mediated intermolecular recombination event.

* Corresponding author. Mailing address: Dept. Microbiología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, P-12, Capital Federal, Argentina. Phone: 54 11 5950-9500, ext. 2171. Fax: 54 11 4964-2554. E-mail: dcentron{at}fmed.uba.ar.

Antimicrobial Agents and Chemotherapy, December 2005, p. 5179-5181, Vol. 49, No. 12
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.12.5179-5181.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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