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Antimicrobial Agents and Chemotherapy, April 2005, p. 1561-1563, Vol. 49, No. 4
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.4.1561-1563.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Penicillin-Binding Proteins in the Pathogenic Intestinal Spirochete Brachyspira pilosicoli{dagger}

Rohana P. Dassanayake,1 Gautam Sarath,2 and Gerald E. Duhamel1*

Department of Veterinary and Biomedical Sciences, University of Nebraska—Lincoln,1 USDA Agricultural Research Division, Lincoln, Nebraska2

Received 10 September 2004/ Returned for modification 9 October 2004/ Accepted 6 December 2004

Penicillin-binding proteins (PBPs) of slightly different molecular masses (94, 62 or 68, 42 or 50, 25, and 22 kDa) were identified in one human and two porcine Brachyspira pilosicoli strains. Identification of PBPs of B. pilosicoli provides a basis for characterization of the genes encoding these proteins among pathogenic intestinal spirochetes of humans and animals.

* Corresponding author. Mailing address: Rm. 147, VBS Bldg., Department of Veterinary and Biomedical Sciences, University of Nebraska—Lincoln, Lincoln, NE 68583-0905. Phone: (402) 472-3862. Fax: (402) 472-9690. E-mail: gduhamel1{at}unl.edu.

{dagger} Published as Paper No. 14743, Agriculture Research Division, Institute for Agriculture and Natural Resources, University of Nebraska—Lincoln, Lincoln, Nebr.

Antimicrobial Agents and Chemotherapy, April 2005, p. 1561-1563, Vol. 49, No. 4
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.4.1561-1563.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Mortimer-Jones, S. M., Phillips, N. D., La, T., Naresh, R., Hampson, D. J. (2008). Penicillin resistance in the intestinal spirochaete Brachyspira pilosicoli associated with OXA-136 and OXA-137, two new variants of the class D {beta}-lactamase OXA-63. J Med Microbiol 57: 1122-1128 [Abstract] [Full Text]  
  • Meziane-Cherif, D., Lambert, T., Dupechez, M., Courvalin, P., Galimand, M. (2008). Genetic and Biochemical Characterization of OXA-63, a New Class D {beta}-Lactamase from Brachyspira pilosicoli BM4442. Antimicrob. Agents Chemother. 52: 1264-1268 [Abstract] [Full Text]  


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