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Antimicrobial Agents and Chemotherapy, July 2005, p. 3056-3058, Vol. 49, No. 7
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.7.3056-3058.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of Levofloxacin and Comparable Agents against Middle Ear Fluid, Nasopharyngeal, and Oropharyngeal Pathogens Obtained from Costa Rican Children with Recurrent Otitis Media or Failing Other Antibiotic Therapy

Carolina Soley,1 Adriano Arguedas,1,2* Wendy Porras,1 Silvia Guevara,1 Cecilia Loaiza,1 Alexandra Pérez,1 Guillermo Rincón,1 Malka Schultz,1 Jorge Arguedas,1 and Roberto Brilla3

Instituto de Atención Pediátrica,1 Universidad de Ciencias Médicas,2 Laboratorio Centro de Investigaciones Médicas, San José, Costa Rica3

Received 21 January 2005/ Returned for modification 16 February 2005/ Accepted 24 March 2005

This study analyzes the in vitro activities of levofloxacin and other commonly used antimicrobials against middle ear fluid, nasopharyngeal, and oropharyngeal pathogens obtained from children with otitis media at risk of having a resistant pathogen. Levofloxacin proved to be very active against these pathogens and had intermediate activity against Streptococcus pyogenes.

* Corresponding author. Mailing address: Instituto de Atención Pediátrica, P.O. Box 607-1150, San José, Costa Rica. Phone: (506) 222-9234. Fax: (506) 221-3894. E-mail: aarguedas{at}iped.net.

Antimicrobial Agents and Chemotherapy, July 2005, p. 3056-3058, Vol. 49, No. 7
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.7.3056-3058.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Stone, K. C., Dagan, R., Arguedas, A., Leibovitz, E., Wang, E., Echols, R. M., Janjic, N., Critchley, I. A. (2007). Activity of Faropenem against Middle Ear Fluid Pathogens from Children with Acute Otitis Media in Costa Rica and Israel. Antimicrob. Agents Chemother. 51: 2230-2235 [Abstract] [Full Text]  


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